VEGF, Vascular endothelial growth factor

• Catalog number
  AS10 1575
• Price
  Please ask
• Size
  0.2 mg

• Available ordering format
  Liquid in 0.9% NaCl, 0.02% sodium azide
• Immunogen
  KLH-conjugated synthetic peptide: APMAEGGGQNHHEVVKF, corresponding to aa 27-43 of human VEGF. Accesion number P15692.
• Raised in
  Chicken
• Clonality
  Polyclonal
• Clone
  Polyclonal
• Purification
  Total IgY
• How to reconstitute
  See included datasheet or contact our support service
• Storage condition
  4 to 8°C
• Verified applications
  direct ELISA (ELISA), immunohistochemistry (IHC)
• Connected products
  AS10 1571 | Anti-VEGFR1 | Vascular endothelial growth factor receptor 1AS10 1578 | Anti-VEGFR2 | Vascular endothelial growth factor receptor 2AS10 1574 | Anti-VEGFR 3 | Vascular endothelial growth factor receptor 3secondary antibodies
• Recommended dilutions for use
  1:2700 (ELISA), 1:1000 (IHC)
• Molecular weight expected аpparent
  27 kDa
• Verified reactivity
  human
• Possible reactivity
  macaque , baboon, bovine
• No reactivity
  no confirmed exceptions from predicted reactivity known in the moment
• Supplementary information
  ELISA has been done with peptide used to elicit this antibody. IHC has been done on paraffin embedded sections.
• References
  to be added when available
• Scientific context
  VEGF | Vascular endothelial growth factor is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. When VEGF is overexpressed, it can contribute to disease. Cancers that can express VEGF are able to grow and metastasize. VEGF is sometimes referred to as vascular permeability factor.
• Notes
  will be added when available
• Protein number
  P15692
• TAIR number
  Refer to NCBI
• Hyperlink
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

• Gene target
  VEGF   Vascular   endothelial   growth   factor  
• Gene symbol
  VEGFA, VEGFC, VEGFD
• Short name
  VEGF, Vascular endothelial growth factor
• Alternative name
  VEGF, Vascular endothelial growth factor
• Tissue
  vascular

Gene info

• Identity
  HGNC:12680
• Gene
  VEGFA
• Long gene name
  vascular endothelial growth factor A
• Synonyms gene
  • VEGF
• Synonyms gene name
  • vascular endothelial growth factor
• Synonyms
  • VEGF-A
  • VPF
• GenBank acession
  • AB021221
• Locus
  6p21.1
• Discovery year
  1994-01-10
• Entrez gene record
  7422
• Pubmed identfication
  • 8786112
• RefSeq identity
  • NM_001025366
• Classification
  • VEGF family
• VEGA ID
  OTTHUMG00000014745
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:12682
• Gene
  VEGFC
• Long gene name
  vascular endothelial growth factor C
• Synonyms
  • VRP
  • VEGF-C
• Synonyms name
  • vascular endothelial growth factor-related protein
• GenBank acession
  • BC035212
• Locus
  4q34.3
• Discovery year
  1996-10-26
• Entrez gene record
  7424
• Pubmed identfication
  • 8617204
• RefSeq identity
  • NM_005429
• Classification
  • VEGF family
• VEGA ID
  OTTHUMG00000160734

Gene info

• Identity
  HGNC:3708
• Gene
  VEGFD
• Long gene name
  vascular endothelial growth factor D
• Synonyms gene
  • FIGF
• Synonyms gene name
  • c-fos induced growth factor (vascular endothelial growth factor D)
• Synonyms
  • VEGF-D
• GenBank acession
  • AJ000185
• Locus
  Xp22.2
• Discovery year
  1997-03-27
• Entrez gene record
  2277
• Pubmed identfication
  • 9479493
• RefSeq identity
  • NM_004469
• Classification
  • VEGF family
• VEGA ID
  OTTHUMG00000021175
• Locus Specific Databases
  • Global Variome shared LOVD

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