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AMBP, Bikunin

  • Catalog number
    AS04 040
  • Product name
    AMBP, Bikunin
  • Size
    200 µl
  • Price
    Ask For Price
  • Contact us
    AMBP, Bikunin
  • Available ordering format
    Lyophilized
  • Immunogen
    Recombinant mouse bikunin purified from baculovirus infected insect cell cultures
  • Raised in
    Rabbit
  • Clonality
    Polyclonal
  • Clone
    Polyclonal
  • Purification
    Serum
  • How to reconstitute
    For reconstitution add 200 µl of sterile water
  • Storage condition
    store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
  • Verified applications
    Western blot (WB), ELISA (ELISA), immunohistochemistry (IHC)
  • Connected products
    AS04 039 | anti-rat bikuninAS06 173 | anti-human bikuninSecondary antibodies
  • Recommended dilutions for use
    1: 2000 (ELISA ), use at an assay dependent dilution (IHC)
  • Molecular weight expected аpparent
    Free bikunin appears as a smear between 60-80 kDa, because the protein core carries sulfated proteoglycans.The most common bikunin complexes are called pre-alpha-inhibitor (PaI) and inter-alpha-inhibitor (IaI) and appears as approximately 120 and 180 kDa.
  • Verified reactivity
    mice
  • Possible reactivity
    rat
  • No reactivity
    no confirmed exceptions from predicted reactivity known in the moment
  • Supplementary information
    Contact Gentaur support center at [email protected]
  • References
    Sánchez et al. (2002). Expression of the AMBP gene transcript and its two protein products, alpha(1)-microglobulin and bikunin, in mouse embryogenesis. Mech Dev. 2002 Sep;117(1-2):293-8.
  • Scientific context
    Bikunin is a Kunitz-type protease inhibitor synthesized in the liver. The AMBP gene resides in the lipocalin cluster and encodes alpha-1-microglobulin together with a Kunitz-type proteinase inhibitor, bikunin. The gene is translated into the alpha-1-microglobulin-bikunin precursor, which is subsequently cleaved and the two proteins are secreted to the blood separately. Bikunin exhibits anti-inflammatory activity in protection against cancer and inflammation.
  • Notes
    This antibody is also reacting with the AMBP precursor.
  • Protein number
    Refer to NCBI
  • TAIR number
    Refer to NCBI
  • Hyperlink
    Hyperlink
  • Alternative to gene target
    • [ "alpha-1-microglobulin/bikunin precursor", "A1M and EDC1 and HCP and HI30 and IATIL and ITI and ITIL and ITILC and UTI", "AMBP and IDBG-81952 and ENSG00000106927 and 259", "calcium oxalate binding", "Extracellular", "Ambp and IDBG-154074 and ENSMUSG00000028356 and 11699", "AMBP and IDBG-638444 and ENSBTAG00000015676 and 280996" ]
  • Gene target
    AMBP Bikunin
    • Gene info
  • Gene symbol
    AMBP
  • Short name
    AMBP, Bikunin