Akt, alpha serine/threonine-protein kinase
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Catalog numberAS16 4007
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PricePlease ask
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Size100 µg
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Available ordering formatLiquid
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ImmunogenRecombinant human Interleukin 10 and P3X63-AG8.653 myeloma cells. UniProt: P31749
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Raised inMouse
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ClonalityMonoclonal
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Clone9Q7, IgG3
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PurificationAffinity purified.
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How to reconstituteSee included datasheet or contact our support service
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Storage conditionStore at -20°C.
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Verified applicationsWestern Blot (WB)
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Connected productsanti-mouse secondary antibodies
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Recommended dilutions for useOptimal concentrations should be determined by serial dilutions.
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Molecular weight expected аpparentsee datasheet
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Verified reactivityHuman, Mouse, Rat
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Possible reactivityto be determined
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No reactivityNo confirmed exceptions from predicted reactivity known at the moment.
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Supplementary informationContact Gentaur support center at [email protected]
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ReferencesTo be added when available, antibody released in November 2016.
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Scientific contextAkt is a serine/threonine kinase that plays an important role in many biological processes like metabolism, cell survival and growth. Akt is activated by the protein PI3K, which then interact with other cytoskeletal proteins. AKT/PKB is active in various types of cancer, and by promoting cell invasiveness and angiogenesis it contributes to tumor progression.
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NotesProvided as sterile filtered solution in phosphate buffered saline pH 7.2.
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Protein numberP31749
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TAIR numberRefer to NCBI
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DescriptionThe Akt, alpha serine/threonine-protein kinase is a α- or alpha protein sometimes glycoprotein present in blood. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.
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Gene target
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Gene symbolAKT1
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Short nameAkt, alpha serine/threonine-protein kinase
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Alternative nameAkt, a serine/threonine-protein phosphorylation catalyst
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Gene info
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Identity
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Gene
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Long gene nameAKT serine/threonine kinase 1
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Synonyms gene name
- v-akt murine thymoma viral oncogene homolog 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
- AKT kinases
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VEGA ID
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Locus Specific Databases