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proBNP Antibody

  • Catalog number
    bs-13389R-FITC
  • Product name
    Glucosidase 2 subunit beta Antibody, FITC Conjugated
  • Size
    0.1ml
  • Short name
    Anti-Glucosidase 2 subunit beta
  • Long name
    Glucosidase 2 subunit beta Antibody, FITC Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    FITC
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Glucosidase 2 subunit beta
  • Specificity
    This is a highly specific antibody against Glucosidase 2 subunit beta.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic peptide derived from human Glucosidase 2 subunit beta
  • Gene ID number
    5589
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum (ER). Glucosidase II is an ER-localized enzyme that contains a and b subunits (Glucosidase IIa and Glucosidase IIb) which form a defined heterodimeric complex. Glucosidase IIa is the catalyitc core of the enzyme and can function independently of the b subunit. The sequence of Glucosidase IIb encodes protein rich in glutamic and aspartic acid with a putative ER retention signal (HDEL) at the C-terminus. The phosphorylated form of Glucosidase IIb is localized in the plasma membrane and is highly expressed in FGF-stimulated fibroblasts and epidermal carcinoma cells. Glucosidase IIb was first purified from a human carcinoma cell line as a potential substrate for protein kinase C. Through the HDEL signal at the C-terminus, Glucosidase IIb retains the complete complex in the ER.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    494nm/518nm
  • Synonyms
    80K-H protein; AGE-binding receptor 2; AGE-R2; G19P1; GLU2B_HUMAN; Glucosidase 2 subunit beta; Glucosidase II beta subunit; Glucosidase II subunit beta; Hepatocystin; PCLD; PKCSH; PLD1; PRKCSH; Protein kinase C substrate 60.1 kDa protein heavy chain; Protein kinase C substrate 80 Kda protein; Protein kinase C substrate 80K-H; Protein kinase C substrate, 80 Kda protein.
  • Gene target
    Glucosidase 2 subunit beta Conjugated
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    FITC
  • label filter
    • FITC
  • technique filter
    • Antibody
    • FITC
  • Technique
    Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
  • Alternative technique
    antibodies, fluorescine