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Coagulation Factor XII Antibody

  • Catalog number
    GENTObs-2210R-A594
  • Product name
    Anti-p38 MAPK (Thr180 + Tyr182), ALEXA Fluor 594
  • Size
    100 microliters
  • Short name
    Anti-p38 MAPK (Thr180 + Tyr182)
  • Type
    Conjugated Primary Antibody
  • Conjugated with
    ALEXA FLUOR® 594
  • Host organism
    Rabbit (Oryctolagus cuniculus)
  • Target Protein Peptide
    p38 MAPK Thr180 + Tyr182
  • Specificity
    This antibody reacts specifically with p38 MAPK (Thr180 + Tyr182)
  • Modification
    Phosphorylation
  • Modification site
    Thr180 + Tyr182
  • Clonality
    Polyclonal Antibody
  • Clone
    Polyclonal Antibodies
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Subcellular locations
    Cytoplasm, Nucleus
  • Antigen Source
    KLH conjugated synthetic phosphopeptide derived from human p38 MAPK around the phosphorylation site of(Thr180/Tyr182)
  • Gene ID
    1432
  • Swiss Prot
    Q16539
  • Applications
    IF(IHC-P)
  • Applications with corresponding dilutions
    IF(IHC-P)(1:50-200)
  • Cross reactive species
    Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Goat
  • Cross Reactive Species details
    No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
  • Background information
    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Purification method
    Purified by Protein A.
  • Storage
    Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Excitation emission
    590nm/617nm
  • Synonyms
    RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated protein kinase 2a; MAPK14
  • Also known as
    p38 MAPK (Thr180 + Tyr182) Antibody
  • Other name
    Anti-p38 MAPK (Thr180 + Tyr182)
  • Advisory
    Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Gene target
    p38 MAPK Thr180 + Tyr182
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    ALEXA FLUOR 594
  • label filter
    • ALEXA FLUOR 594
  • technique filter
    • anti-
    • anti
  • Technique
    anti-, anti, antibody to, antibodies
  • Alternative technique
    antibodies