EcoCRM™ Diptheria Toxin CRM197 Mutant Vaccine Carrier Protein

Lot number

NO9p157
Description

EcoCRM™ is CRM197 produced as a soluble intracellular protein in E. coli. CRM197 is genetically detoxified diphtheria toxin. Specifically, it has a single amino acid substitution (glycine52 to glutamic acid), which causes the ADPribosyltransferase activity to be lost. CRM197 is widely used as the carrier protein for conjugate vaccines. EcoCRM™ is expressed as a recombinant protein in Escherichia coli
Virus category

Vaccine Adjuvant
Type

other
Viral target

Diphteria Toxin
Raised in

N/A
Clonality

N/A
Applications

Enzyme-Linked Immunosorbent Assay, SDS-PAGE
Storage

-80°C, avoid repeated freeze/thaws
Techfile
Virus detection
Additional description

A carrier can hold protected the subject it is supporting for the period needed by its application as stated by virus detection.

Gene target

EcoCRM™ Diptheria CRM197 Mutant Vaccine Protein
Short name

EcoCRM™ Diptheria CRM197 Mutant Vaccine Protein
Alternative name

EcoCRM™ Diptheria Toxin CRM197 Mutant immunization Carrier Protein

Name

Radioallergosorbent Test
Concept

Scope note: An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
Tree numbers
- E01.370.225.812.735.830
- E05.200.812.735.830
- E05.478.566.380.810
- E05.478.566.639.810
- E05.478.594.760.830
- E05.601.470.380.810
- E05.601.470.639.810
Qualifiers

ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data