Purified GST-tagged human RAR-related orphan receptor alpha ligand binding domain
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Catalog numberN1F1-50
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PricePlease ask
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Size50 μg
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DescriptionPurified GST-tagged human RAR-related orphan receptor alpha ligand binding domain is used mainly for ligand-binding and coregulator displacement assays
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Produced inNA
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ApplicationDrug discovery, Nuclear receptors, purified recombinant protein
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Gene number6095
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DeliveryShipped under dry ice. Additional shipping fee will be made.
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StorageStore at minus 80°C
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Technical filePlease inquire the latest datasheet, protocol, certificate of analysis or SDS
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Additional descriptionThe RORA-LBD is a α- or alpha protein sometimes glycoprotein present in blood. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbolRARA, MGST3, RAB40B, PRAM1, RAB40A
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Short nameRORA-LBD
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Techniquepurified, purifications
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SpeciesHuman, Humans
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Alternative nameenriched GST-tagged H. sapiens RAR-related orphan receptor a ligand binding domain
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Alternative techniquepure
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Gene info
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Identity
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Gene
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Long gene nameretinoic acid receptor alpha
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Synonyms gene name
- retinoic acid receptor, alpha
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Synonyms
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GenBank acession
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Locus
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Discovery year1988-06-09
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Entrez gene record
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Pubmed identfication
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Classification
- Retinoic acid receptors
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemicrosomal glutathione S-transferase 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-10-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Microsomal glutathione S-transferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAB40B, member RAS oncogene family
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-02-22
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Entrez gene record
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Pubmed identfication
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Classification
- RAB, member RAS oncogene GTPases
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePML-RARA regulated adaptor molecule 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-07-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAB40A, member RAS oncogene family
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-02-22
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Entrez gene record
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Pubmed identfication
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Classification
- RAB, member RAS oncogene GTPases
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VEGA ID
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Locus Specific Databases