Purified GST-tagged human Estrogen receptor alpha LBD in complex with Hsp90
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Catalog number
SG90-50
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Price
Please ask
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Size
50 μg
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Description
Purified GST-tagged human Estrogen receptor alpha LBD in complex with Hsp90 is used mainly for ligand-binding and coregulator displacement studies
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Produced in
NA
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Application
Drug discovery, Nuclear receptors, purified recombinant protein
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Gene number
2908
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Delivery
Shipped under dry ice. Additional shipping fee will be made.
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Storage
Store at minus 80°C
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Technical file
Please inquire the latest datasheet, protocol, certificate of analysis or SDS
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Additional description
The GR-LBD is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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