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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
188062-50-2
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Chemical s molecular weight
670.74
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Chemical s main applications
Abacavir Sulfate is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
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Chemical s category
Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
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Other name
(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Sulfate; Ziagen;
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Chemical s formula
C28H38N12O6S
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Physical properties
White to Off-White Solid
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Melting temperature
213 - 214°C (dec.)
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Boiling temperature
No Data Available
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Chemical s soluble in
Water, Methanol (Sparingly)
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Stability conditions
No Data Available
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Storage
-20°C Freezer
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