TPCK, Serine protease inhibitor

• Catalog number
  SIH-207-500MG
• Price
  Please ask
• Size
  500 mg

• Stock availabilitIn Stock
  In Stock
• CAS number
  402-71-1
• Description
  Serine protease inhibitor
• Molecular weight
  351,85 g/mol
• Primary research fields
  Cancer, Apoptosis
• Other name
  N-(4-Chloro-3-oxo-1-phenyl-2-butanyl)-4-methylbenzenesulfonamide
• Product category
  Small Molecules
• Product type
  Inhibitor
• Chemical formula
  C17H18CI3O3S
• Origin
  Synthetic
• Purity pourcentage
  >98%
• Soluble in
  Soluble in DMSO (>10 mg/ml) and in 10 mM in methanol and ethanol (50 mg/ml)
• Physical appearance
  White Solid
• Storage recommendations
  -20ºC
• Shipping recommendations
  Shipped Ambient
• Safety information
  Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: 37/38-41 Hazard Phrases: H315-H318-H335 Precautionary Phrases: P261-P280-P305 + P351 + P338
• PubChem number
  9824
• Scientific context
  Tosyl phenylalanyl chloromethyl ketone is a protease inhibitor. It also inhibits some cysteine proteases (1).
• Bibliography
  1. Farrelll S.O., Campbell M.K. (2006) Biochemistry. Australia: Thomson Brooks/Cole. P.160.
• Release date
  16-May-2011
• PubMed number
  Refer to PubMed
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• Representative figure link
• Representative figure legend
  Chemical structure of TPCK (SIH-207), a Serine protease inhibitor. CAS #: 402-71-1. Molecular Formula: C17H18CI3O3S. Molecular Weight: 351.85 g/mol. Chemical structure of TPCK, a Serine protease inhibitor (SIH-207). CAS # 402-71-1. Molecular Formula: C17H18CI3O3S.
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  0.25
• Net weight g
  0.5
• Other related products
• Additional description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.

• Gene target
  TPCK   Serine   protease   inhibitor  
• Short name
  TPCK, Serine protease inhibitor
• Alternative name
  TPCK, Serine protease suppressor

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