anti-NOX2 Antibody

  • Catalog number
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX2, also known as cytochrome b beta (CYBB) is one of two proteins that make up Cytochrome b-245, thought to be a primary component of the microbicidal oxidase system of phagocytes. NOX2 deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD) (2). Activation of the NOX2 enzyme complex in microglia is thought to be neurotoxic and may play a role in Alzheimer’s and Parkinson’s disease (3).
  • Gene names
    NOX2 Antibody: CGD, NOX2, AMCBX2, GP91-1, GP91PHOX, p91-PHOX, GP91-PHOX, Cytochrome b-245 heavy chain, CGD91-phox, Cytochrome b558 subunit beta
  • Antibodie s label
    unlabelled serum
  • Purity
    NOX2 antibody is affinity chromatography purified via peptide column.
  • Ab raised in
  • Type
  • Immunoglobulin
  • Spicific to
    NOX2 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will detect both isoforms. NOX2 is predicted to not cross-react with other NOX proteins.
  • Antigen
    Rabbit polyclonal NOX2 antibody was made against a 15 amino acid peptide near the amino terminus of human NOX2.
  • Immuno application
    ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
  • Antibody advice
    NOX2 antibody can be used for detection of NOX2 by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
  • Suspention pH azide
    NOX2 antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    NOX2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
  • Works with
    Human, Mouse, Rat
  • Omim nr
  • Ncbi nr
  • KDa
    Predicted: 59, 63 kDa Observed: 58 kDa
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
  • GENE symbol
  • Antigene name
    cytochrome b-245, beta polypeptide
  • Source
    homo sapiens
  • Protein nr
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
  • Gene target
  • Gene symbol
  • Short name
    anti-NOX2 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toNOX2 (antibody to-)
  • Alternative technique
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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