anti-Huntington Protein Antibody

Gene info

Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (Htt) protein. The disease is characterized by neurodegeneration and formation of neuronal intracellular inclusions primarily in the striatum and cortex, leading to personality changes, motor impairment, and dementia. The Huntington’s disease protein is ~350 kDa in size and is localized in the brain.
Gene names

HD, IT15, HD
Antibodie s label

unlabelled serum
Purity

Affinity Purified
Ab raised in

Rabbit
Type

Polyclonal
Immunoglobulin

IgG
Antigen

A synthetic peptide corresponding to the N-terminus.
Immuno application

ELISA, Western Blot, immuno-histo-chemistry
Antibody advice

ELISA, Western (immuno) blotting, Immunostaining (in testing)
Works with

Human, Mouse, Rat
Omim nr

296434520
Ncbi nr

AAB38240
NCBI GENE nr

3064
GENE symbol

HTT
Antigene name

huntingtin
Source

Homo sapiens
Protein nr

P42858
Picture
Pdf tech file
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Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation

anticorps

Gene target

Huntington Protein
Short name

anti-Huntington Protein Antibody
Technique

Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
Alternative name

Antibody toHuntington Protein (antibody to-)
Alternative technique

antibodies
Disease

huntington

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data