anti-FGG Antibody
-
Catalog number29-981
-
PricePlease ask
-
Size100 ug
-
-
Gene infoFGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
-
Gene namesFGG,
-
Antibodie s labelunlabelled serum
-
PurityAntibody is purified by protein A chromatography method.
-
Ab raised inRabbit
-
TypePolyclonal
-
AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FGG.
-
Immuno applicationELISA, Western Blot
-
Antibody adviceFGG antibody can be used for detection of FGG by ELISA at 1:312500. FGG antibody can be used for detection of FGG by western blot at 2.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
-
Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store FGG antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
-
Works withHuman, Mouse, Rat, Dog
-
Omim nr70906437
-
Ncbi nrNP_000500
-
KDa46 kDa, 52 kDa
-
Vial with antibodyLyophilized
-
Quantity per ml1 mg/ml
-
NCBI GENE nr2266
-
GENE symbolFGG
-
Antigene namefibrinogen gamma chain
-
SourceHomo sapiens
-
Protein nrQ53Y18
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolFGG
-
Short nameanti-FGG Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative nameAntibody toFGG (antibody to-)
-
Alternative techniqueantibodies
-
Alternative to gene targetfibrinogen gamma chain, FGG and IDBG-42165 and ENSG00000171557 and 2266, protein binding, Extracellular, Fgg and IDBG-154510 and ENSMUSG00000033860 and 99571, FGG and IDBG-628944 and ENSBTAG00000006745 and 280792
-
Gene info
-
Identity
-
Gene
-
Long gene namefibrinogen gamma chain
-
Synonyms gene name
- fibrinogen, gamma polypeptide
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
RefSeq identity
-
Classification
- Fibrinogen C domain containing
- Receptor ligands
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data