anti-DR4 Antibody

  • Catalog number
    1167
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    DR4 Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells.
  • Gene names
    DR4 Antibody: DR4, APO2, CD261, TRAILR1, TRAILR-1, DR4, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TRAIL receptor 1
  • Antibodie s label
    unlabelled serum
  • Purity
    DR4 Antibody is Antibody is DEAE purified.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Spicific to
    DR4 antibody has no cross reaction to DR5.
  • Antigen
    DR4 antibody was made against a 20 amino acid peptide near the amino terminus of human DR4.
  • Immuno application
    ELISA, Western Blot
  • Antibody advice
    DR4 antibody can be used for detection of DR4 by Western blot 0.5 ug/mL. A 57 kDa band can be detected.
  • Suspention pH azide
    DR4 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    DR4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human
  • Omim nr
    1945072
  • Ncbi nr
    AAC51226
  • KDa
    57 kDa
  • Vial with antibody
    in solution
  • NCBI GENE nr
    8797
  • GENE symbol
    TNFRSF10A
  • Antigene name
    tumor necrosis factor receptor superfamily, member 10a
  • Source
    Homo sapiens
  • Protein nr
    O00220
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    DR4  
  • Gene symbol
    TNFRSF10A
  • Short name
    anti-DR4 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toDR4 (antibody to-)
  • Alternative technique
    antibodies
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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