anti-DR4 Antibody
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Catalog number1167
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoDR4 Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells.
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Gene namesDR4 Antibody: DR4, APO2, CD261, TRAILR1, TRAILR-1, DR4, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TRAIL receptor 1
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Antibodie s labelunlabelled serum
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PurityDR4 Antibody is Antibody is DEAE purified.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toDR4 antibody has no cross reaction to DR5.
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AntigenDR4 antibody was made against a 20 amino acid peptide near the amino terminus of human DR4.
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Immuno applicationELISA, Western Blot
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Antibody adviceDR4 antibody can be used for detection of DR4 by Western blot 0.5 ug/mL. A 57 kDa band can be detected.
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Suspention pH azideDR4 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atDR4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman
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Omim nr1945072
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Ncbi nrAAC51226
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KDa57 kDa
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Vial with antibodyin solution
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NCBI GENE nr8797
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GENE symbolTNFRSF10A
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Antigene nametumor necrosis factor receptor superfamily, member 10a
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SourceHomo sapiens
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Protein nrO00220
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTNFRSF10A
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Short nameanti-DR4 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toDR4 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 10a
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 10a
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Tumor necrosis factor receptor superfamily
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data