anti-CCR5 Antibody

• Catalog number
  1112
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  CCR5 Antibody: Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The beta-chemokines RANTES, MIP-alpha and MIP-beta are the ligands for CCR5 and prevent infection by M-tropic HIV-1. CXC5 associates with the surface CD4-gp120 of HIV complex and leads to membrane fusion and virus entry of target cells. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV biding sites. CCR5 messenger RNA is expressed in lymphoid organs and monocytes.
• Gene names
  CCR5 Antibody: CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5, C-C chemokine receptor type 5, CHEMR13, C-C CKR-5
• Antibodie s label
  unlabelled serum
• Purity
  CCR5 Antibody is Antibody is DEAE purified.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  CCR5 antibody was made against a 15 amino acid peptide near the amino terminus of human CCR5.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  CCR5 antibody can be used for Western blot at 1:1000 dilution. An approximate 40 kDa band can be detected. CCR5 antibody can also detect CCR5 by immunohistochemistry at 20 ug/mL.
• Suspention pH azide
  CCR5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  CCR5 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  2104520
• Ncbi nr
  AAB57793
• KDa
  40 kDa
• Vial with antibody
  in solution
• NCBI GENE nr
  1234
• GENE symbol
  CCR5
• Antigene name
  chemokine (C-C motif) receptor 5
• Source
  Homo sapiens
• Protein nr
  P51681
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCR5  
• Gene symbol
  CCR5
• Short name
  anti-CCR5 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCCR5 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) receptor 5 (gene/pseudogene), CC-CKR-5 and CCCKR5 and CCR-5 and CD195 and CKR-5 and CKR5 and CMKBR5 and IDDM22, CCR5 and IDBG-30229 and ENSG00000160791 and 1234, chemokine (C-C motif) ligand 5 binding, Cell surfaces, CCR5 and IDBG-646247 and ENSBTAG00000008099 and 497017

Gene info

• Identity
  HGNC:1606
• Gene
  CCR5
• Long gene name
  C-C motif chemokine receptor 5
• Synonyms gene
  • CMKBR5
• Synonyms gene name
  • chemokine (C-C motif) receptor 5
  • chemokine (C-C motif) receptor 5 (gene/pseudogene)
  • C-C motif chemokine receptor 5 (gene/pseudogene)
• Synonyms
  • CKR-5
  • CC-CKR-5
  • CKR5
  • CD195
  • IDDM22
• Locus
  3p21.31
• Discovery year
  1996-05-15
• Entrez gene record
  1234
• Pubmed identfication
  • 8639485
  • 9284370
  • 20210993
• RefSeq identity
  • NM_000579
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000133481

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products