anti-Bim Antibody
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Catalog number2065
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoBim Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat. Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
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Gene namesBim Antibody: BAM, BIM, BOD, Bcl-2-like protein 11, Bcl2-interacting mediator of cell death, Bcl2-L-11
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Antibodie s labelunlabelled serum
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PurityBim Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenBim antibody was made against a 20 amino acid peptide corresponding to amino acids near the amino terminus of human Bim.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry
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Antibody adviceBim antibody can be used for detection of Bim by Western blot at 1 ug/mL. A 23 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 20 ug/mL.
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Suspention pH azideBim Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atBim antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr18202042
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Ncbi nrO43521
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KDa23 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr10018
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GENE symbolBCL2L11
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Antigene nameBCL2-like 11 (apoptosis facilitator)
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SourceHomo sapiens
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Protein nrO43521
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolBCL2L11, MIR4435-2HG
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Short nameanti-Bim Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toBim (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameBCL2 like 11
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Synonyms gene name
- BCL2-like 11 (apoptosis facilitator)
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-12-10
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Entrez gene record
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Pubmed identfication
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Classification
- BCL2 homology region 3 (BH3) only
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameMIR4435-2 host gene
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Synonyms gene
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Synonyms gene name
- MIR4435-1 host gene (non-protein coding)
- MIR4435-1 host gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2013-07-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA non-coding host genes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data