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Gene info
Bid Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bid, a pro-apoptotic Bcl-2 family member, is cleaved by caspase-8 in response to apoptotic signals, exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein. The cleaved complex is myris-toylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize.
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Gene names
Bid Antibody: FP497, BH3-interacting domain death agonist, p22 BID, BID
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Antibodie s label
unlabelled serum
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Purity
Bid Antibody is Ion exchange chromatography purified.
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Ab raised in
Rabbit
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Type
Polyclonal
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Immunoglobulin
IgG
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Antigen
Bid antibody was made against a peptide corresponding to 14 amino acids near the carboxy terminus of human Bid.
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Immuno application
ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody advice
Bid antibody can be used for detection of Bid by Western blot at 0.5 to 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2 ug/mL. For immunofluorescence start at 10 ug/mL.
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Suspention pH azide
Bid Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
Bid antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human, Mouse
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Omim nr
54673639
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Ncbi nr
AAH36364
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
637
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GENE symbol
BID
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Antigene name
BH3 interacting domain death agonist
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Source
Homo sapiens
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Protein nr
P55957
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
BID
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Short name
anti-Bid Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toBid (antibody to-)
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Alternative technique
antibodies
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Alternative to gene target
BH3 interacting domain death a this GO nist, FP497, BID and IDBG-1050 and ENSG00000015475 and 101929618,637, ubiquitin protein ligase binding, Plasma membranes, Bid and IDBG-184076 and ENSMUSG00000004446 and 12122, BID and IDBG-641320 and ENSBTAG00000013988 and 510373,782484
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