anti-ADAM10 Antibody
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Catalog number2051
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoADAM10 Antibody: Proinflammatory cytokine tumor necrosis factor-alpha (TNF-a;) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a;, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a;, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.
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Gene namesADAM10 Antibody: RAK, kuz, AD10, AD18, MADM, CD156c, HsT18717, KUZ, Disintegrin and metalloproteinase domain-containing protein 10, CDw156, ADAM 10
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Antibodie s labelunlabelled serum
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PurityADAM10 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenADAM10 antibody was made against a 17 amino acid peptide near the carboxy terminus of human ADAM10.
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Immuno applicationELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence
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Antibody adviceADAM10 can be used for detection of ADAM10 by Western blot at 1 - 2 ug/mL. This polyclonal antibody can also detect ADAM10 by immunohistochemistry at 2 ug/mL. For immunofluorescence start at 10 ug/mL.
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Suspention pH azideADAM10 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atADAM10 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman
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Omim nr4557251
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Ncbi nrNP_001101
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KDa85 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr102
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GENE symbolADAM10
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Antigene nameADAM metallopeptidase domain 10
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SourceHomo sapiens
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Protein nrO14672
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolADAM10
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Short nameanti-ADAM10 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toADAM metallopeptidase domain 10 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetADAM metallopeptidase domain 10, AD10 and AD18 and CD156c and HsT18717 and kuz and MADM and RAK, ADAM10 and IDBG-14155 and ENSG00000137845 and 102, protein homodimerization activity, nuclei, Adam10 and IDBG-182594 and ENSMUSG00000054693 and 11487, ADAM10 and IDBG-646594 and ENSBTAG00000005481 and 282132
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Gene info
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Identity
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Gene
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Long gene nameADAM metallopeptidase domain 10
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Synonyms gene name
- a disintegrin and metalloproteinase domain 10
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-03-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ADAM metallopeptidase domain containing
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data