STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF640R conjugate, 0.1mg/mL

CAT: 0037-BNC401907-500Size: 1x 500 µLDry Ice: NoHazardous: No
Product image 1Product image 2
1 / 2
CAT#:0037-BNC401907-500Size:1x 500 µL
Selected
AVAILABILITY: In Stock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
APRF; HIES; ADMIO; ADMIO1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
STAT3
Gene ID
6774
NCBI Gene ID
463059
UniProt
P40763
Swiss Prot
P40763
Host
Mouse
Species Reactivity
Human
Reactivity
STAT3
Immunogen
Recombinant full-length human STAT3 protein
Target Antigen
STAT3
Clonality
Monoclonal
Clone
PCRP-STAT3-2F12
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Immunology, Inflammation, Signal transduction, Transcription factors
Positive Control
A431 and Raji cells. Kidney, Brain or Heart
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
88 kDa
References & Citations
Zhong, Z., et al. 1994. Science 264: 95-98
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R
Product Datasheet
Loading...
Product MSDS
Loading...

Related Products

CatalogName
BNC471907-100STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF647 conjugate, 0.1mg/mL
BNC471907-500STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF647 conjugate, 0.1mg/mL
BNUB1907-100STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), 0.2mg/mL
BNUB1907-500STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), 0.2mg/mL
BNC041907-500STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF405S conjugate, 0.1mg/mL
BNC041907-100STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF405S conjugate, 0.1mg/mL
BNC941907-100STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF594 conjugate, 0.1mg/mL
BNCB1907-500STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), Biotin conjugate, 0.1mg/mL
BNC741907-100STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF740 conjugate, 0.1mg/mL
BNC941907-500STAT3 / Signal Transducer and Activator of Transcription 3 (PCRP-STAT3-2F12), CF594 conjugate, 0.1mg/mL

Alternative Products

CatalogName
A12232-1STAT3-IN-1 1mg
GCCF003FR1MegaFLUO® FITC IgG Conjugate (3.0 ml)
MCH003FR1MegaFLUO® FITC IgM Conjugate (3.0 ml)
65R-S105PHRPStreptavidin Poly-HRP80 Conjugate, 1mg/ml aqueous solution
QP9416-ye-1mgRecombinant Human STAT3 Protein, His, Yeast-1mg
PB9511-Cy3Anti-STAT3 Antibody Picoband® (Cy3 Conjugate)
PB9511-Dylight550Anti-STAT3 Antibody Picoband® (Dylight550 Conjugate)
PB9511-BiotinAnti-STAT3 Antibody Picoband® (Biotine Conjugate)
PB9511-PEAnti-STAT3 Antibody Picoband® (PE Conjugate)
PB9511-Dylight594Anti-STAT3 Antibody Picoband® (Dylight594 Conjugate)

Popular Products