CD44v9 (Marker of Tumor Metastasis) (CD44v9/2344R), CF488A conjugate, 0.1mg/mL

CAT: 0037-BNC882344-500Size: 1x 500 µLDry Ice: NoHazardous: No
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CAT#:0037-BNC882344-500Size:1x 500 µL
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Description
This antibody recognizes an epitope encoded by exon v4 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
LHR; BA-1; chondroitin sulfate proteoglycan 8 (CSPG8) ; Epican; Extracellular Matrix Receptor III (ECM III) ; GP90 Lymphocyte Homing Adhesion Receptor; HCAM; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan Sulfate Proteoglycan; Hermes Antigen; HAS; HUTCH I; Hyaluronate Receptor; Indian blood group; Inlu Related p80 Glycoprotein; Ly 24; MDU2; MDU3; MIC4; MUTCH I; Phagocytic Glycoprotein 1 (PGP-1)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD44
Gene ID
960
NCBI Gene ID
502328
UniProt
P16070
Swiss Prot
P16070
Host
Rabbit
Species Reactivity
Human
Reactivity
CD44v9
Immunogen
Recombinant fragment corresponding to the v9 domain of human CD44
Target Antigen
CD44v9
Clonality
Recombinant Monoclonal
Clone
CD44v9/2344R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Immunology
Positive Control
Cervix or Tongue Squamous Cell Carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
80-95 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A
Product Datasheet
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