SUMO-1 (SUMO1/1188), CF594 conjugate, 0.1mg/mL

CAT: 0037-BNC941188-500Size: 1x 500 µLDry Ice: NoHazardous: No
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CAT#:0037-BNC941188-500Size:1x 500 µL
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Description
This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
GAP-modifying protein 1; GMP1; OFC10; PIC1; SENP2; Sentrin 1; Small ubiquitin-related modifier 1; SMT3; SMT3 suppressor of mif two 3 homolog 1; SMT3C; SMT3H3; Ubiquitin homology domain protein PIC1; Ubiquitin Like 1; Ubiquitin like protein UBL1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SUMO1
Gene ID
7341
NCBI Gene ID
596171
UniProt
P63165
Swiss Prot
P63165
Host
Mouse
Species Reactivity
Human, Rat
Reactivity
SUMO 1
Immunogen
Recombinant human SUMO1 protein
Target Antigen
SUMO 1
Clonality
Monoclonal
Clone
SUMO1/1188
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Sumoylation
Positive Control
Breast carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
11.5 kDa (Monomer) ; 90 kDa (Heteromer)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594
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