Fibronectin (HFN7.1), Biotin conjugate, 0.1mg/mL

CAT: 0037-BNCB0270-100Size: 1x 100 µLDry Ice: NoHazardous: No
CAT#:0037-BNCB0270-100Size:1x 100 µL
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Description
Fibronectin is a dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. It possesses at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectin is involved in cell adhesion, tissue organization, and wound healing. This MAb is directed against the peptide core and reacts with both the plasma and cellular forms of fibronectin. It blocks the fibronectin-medicated cell attachment not by disrupting the collagen-fibronectin interaction, but by interfering with the attachment of fibronectin to its receptor on the cell surface.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
Cold insoluble globulin (CIG) ; FINC; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor (MSF) ; Ugl-Y3
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FN1
Gene ID
2335
NCBI Gene ID
203717
UniProt
P02751
Swiss Prot
P02751
Host
Mouse
Species Reactivity
Human
Reactivity
Fibronectin
Immunogen
Human fibronectin purified from serum by affinity chromatography on gelatin-sepharose
Target Antigen
Fibronectin
Clonality
Monoclonal
Clone
HFN7.1
Type
Primary
Source
Animal
Origin
Animal
Applications
Functional studies (published) |IF (published) |ELISA (published) |IHC, FFPE (verified) |WB (published)
Field of Research
Cell adhesion, Extracellular matrix
Positive Control
SW156 cells or Kidney
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
220 kDa (monomer) ; 440 kDa (dimer)
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Biol Chem (1991) 266(14): 23323-23328. (inhibition of integrin binding; epitope mapping) Anat Rec (1996) 245:068-676. (IF, frozen tissue) PNAS USA (2005) 102(17): 5953-5957. (functional studies) Biomaterials (2005) 26: 4523-4531. (IF; functional studies) Hybridoma (2006) 25(4): 202-208. (ELISA; WB)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin
Product Datasheet
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Product MSDS
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