CD56 / NCAM (NCAM1/784), Biotin conjugate, 0.1mg/mL

This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas) . It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma) . Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

9007-83-4

NCAM, Leu-19, NKH1, MSK39, NCAM120, NCAM140, NCAM180, Neural Cell Adhesion Molecule

41116161

Primary and secondary antibodies for multiple methodology immunostaining detection application

NCAM1

4684

503878

P13591; P13592

P13591 & P13592

CD56|NCAM

Recombinant human NCAM1 protein

CD56 | NCAM

NCAM1/784

Primary

Animal

Animal

IHC, FFPE (verified)

Cancer, Cell adhesion, Neuroscience

Cerebellum, Pancreas, Neuroblastoma

2 years

0.1 mg/mL

PBS, 0.1% BSA, 0.05% azide

180, 145 and 125 kDa

RT (ND)

Stable at room temperature or 37°C (98°F) for 7 days.

Guaranteed for at least 24 months from date of receipt when stored as recommended

IgG1, kappa

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

0.05% sodium azide (CAS 26628-22-8)