CD48 (5-4.8), CF405S conjugate, 0.1mg/mL

CAT: 0037-BNC041057-100Size: 1x 100 µLDry Ice: NoHazardous: No
CAT#:0037-BNC041057-100Size:1x 100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI) -anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
B cell membrane protein; B-cell activation marker; BCM1 surface antigen; BLAST1; Signaling lymphocytic activation molecule 2; SLAM family member 2 (SLAMF2) ; TCT.1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD48
Gene ID
962
NCBI Gene ID
243564
UniProt
P09326
Swiss Prot
P09326
Host
Mouse
Species Reactivity
Human
Reactivity
CD48
Immunogen
Human peripheral blood lymphocytes
Target Antigen
CD48
Clonality
Monoclonal
Clone
5-4.8
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published) |WB (published)
Field of Research
Immunology
Positive Control
Daudi, JY, Raji, Jurkat, and human lymphocytes. Human lymph node and tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
45 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Exp Med (1996) 184: 1769-1779. (functional studies)>/li> J Immunol (2001) 166:5567-5577. (Flow; functional studies; WB)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S
Product Datasheet
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Product MSDS
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