CD15 / FUT4 / Lewis x (FUT4/815), 1mg/mL

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Description
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin's disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance. This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
CAS Number
9007-83-4
Synonyms
3 Fucosyl N Acetyl Lactosamine; Alpha (1,3) Fucosyltransferase; Alpha 13 fucosyltransferase FucT; ELAM Ligand Fucosyltransferase; ELFT; FCT3A; Fuc-TIV; Fucosyltransferase 4 Alpha 1 3 Fucosyltransferase Myeloid Specific; Fucosyltransferase 4; Galactoside 3 L Fucosyltransferase; Lewis X; LeX; SSEA1; Stage Specific Embryonic Antigen 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FUT4
Gene ID
2526
NCBI Gene ID
654379
UniProt
P22083
Swiss Prot
P22083
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
CD15|FUT4|Lewis-x
Immunogen
Purified human neutrophils
Target Antigen
CD15 | FUT4 | Lewis-x
Clonality
Monoclonal
Clone
FUT4/815
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Immunology
Positive Control
U937 cells, Reed-Sternberg's cells in Hodgkin's lymphoma
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
~220 kDa (Glycoprotein)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgM, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free
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C2266-20BCD15 (Alpha- (1,3) -fucosyltransferase, ELAM-1 Ligand Fucosyltransferase, ELAM Ligand Fucosyltransferase, ELFT, FCT3A, Fucosyltransferase 4 (alpha (1,3) Fucosyltransferase Myeloid-specific), FUT4, Fucosyltransferase IV, Fuc-TIV, FucT-IV, FUTIV, Lewis X, LeX, Stage Specific Embryonic Antigen 1, SSEA 1, SSEA-1)
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