Arginase 1 (Hepatocellular Carcinoma Marker) (ARG1/1126), 0.2mg/mL

• Description :

  This antibody recognizes a protein of 35-38 kDa, which is identified as Arginase 1 (ARG1) . Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibodies to Arginase 1 label hepatocytes in normal tissues and granulocytes in peripheral blood. Arginase 1 is a sensitive and specific marker for identification of hepatocellular carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• CAS Number :

  9007-83-4

• Synonyms :

  Arginase 1; ARG1; liver-type arginase; type I arginase

• UNSPSC :

  41116161

• UNSPSC Description :

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name :

  ARG1

• Gene ID :

  383

• NCBI Gene ID :

  440934

• UniProt :

  P05089

• Swiss Prot :

  P05089

• Host :

  Mouse

• Species Reactivity :

  Human

• Reactivity :

  Arginase 1

• Immunogen :

  Recombinant human ARG1 protein fragment (around aa11-97) (exact sequence is proprietary)

• Target Antigen :

  Arginase 1

• Clonality :

  Monoclonal

• Clone :

  ARG1/1126

• Type :

  Primary

• Source :

  Animal

• Origin :

  Animal

• Applications :

  IHC, FFPE (verified)

• Field of Research :

  Cancer, Metabolism

• Positive Control :

  293Tcells. Hepatocellular Carcinoma (HCC).

• Stability :

  2 years

• Concentration :

  0.2 mg/mL

• Buffer :

  PBS, 0.05% BSA, 0.05% azide

• Molecular Weight :

  35-38 kDa

• Shipping Conditions :

  RT (ND)

• Storage Conditions :

  Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life :

  Guaranteed for at least 24 months from date of receipt when stored as recommended

• Fragment :

  IgG3, kappa

• Species :

  Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

• Classification :

  PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

• Conjugate :

  Purified, with BSA