Ac-Trp-Glu-His-Asp-AMC

• UNSPSC Description:

  Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1[1].

• Target Antigen:

  Caspase

• Type:

  Peptides

• Related Pathways:

  Apoptosis

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ac-trp-glu-his-asp-amc.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC=C(C=C1O2)NC([C@H](CC(O)=O)NC([C@H](CC3=CN=CN3)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O)=CC2=O

• Molecular Weight:

  784.77

• References & Citations:

  [1]Kindermann M, et al. Selective and sensitive monitoring of caspase-1 activity by a novel bioluminescent activity-based probe. Chem Biol. 2010 Sep 24;17(9):999-1007.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  189275-74-9