Biotinylated Cynomolgus LAG-3 / CD223 Protein, Mouse IgG2a Fc Tag, ultra sensitivity (primary amine labeling) (MALS verified)

• Background:

  Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

• Description:

  Biotinylated Cynomolgus LAG-3, Mouse IgG2a Fc Tag, primary amine labeling (LA3-C8258) is expressed from human 293 cells (HEK293) . It contains AA Ala 18 - His 449 (Accession # XP_005570011.1) .

• Specifications:

  This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 73.5 kDa. The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

• Accession Number:

  XP_005570011.1

• Expression Region:

  Ala 18 - His 449

• Host:

  HEK293

• Target:

  LAG-3

• Conjugation:

  Biotin-labeled

• Tag:

  C-mFc (mIgG2a)

• Source:

  Cynomolgus

• Stability:

  ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

• Endotoxin:

  1.0 EU per μg

• Purity:

  95%

• Bioactivity:

  Immobilized Biotinylated Cynomolgus LAG-3, Mouse IgG2a Fc Tag, primary amine labeling (Cat. No. LA3-C8258) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Monoclonal Anti-Human LAG3 Antibody, Human IgG1 with a linear range of 0.2-6 ng/mL (QC tested).

• Format:

  Powder

• Buffer:

  PBS, pH7.4

• Additives:

  Trehalose

• Molecular Weight:

  73.5 kDa

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C

• Package Size:

  200ug*1

• Species:

  Cynomolgus