RANTES Recombinant Rabbit Monoclonal Antibody [JM03-45]

• Description:

  Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES (3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES (4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES (1-68) and RANTES (3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.

• Product Name Alternative:

  Beta chemokine RANTES antibody Beta chemokine RANTES precursor antibody C C motif chemokine 5 antibody CCL 5 antibody CCL5 antibody CCL5_HUMAN antibody Chemokine (C C motif) ligand 5 antibody Chemokine CC Motif Ligand 5 antibody D17S136E antibody EoCP antibody Eosinophil chemotactic cytokine antibody MGC17164 antibody RANTES (4-68) antibody Regulated upon activation normally T expressed and presumably secreted antibody SCYA 5 antibody SCYA5 antibody SIS delta antibody SIS-delta antibody SISd antibody Small inducible cytokine A5 (RANTES) antibody Small inducible cytokine A5 antibody Small inducible cytokine subfamily A (Cys Cys) member 5 antibody Small-inducible cytokine A5 antibody T cell specific protein p288 antibody T cell specific RANTES protein antibody T cell-specific protein P228 antibody T-cell-specific protein RANTES antibody TCP 228 antibody TCP228 antibody

• Abbreviation:

  TCP228, CCL5, D17S136E, SCYA5

• Swiss Prot:

  P13501 Human, P30882 Mouse

• Cellular Locus:

  Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant protein within human RANTES aa 1-91.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IHC-P, IF-Cell, IF-Tissue

• Positive Control:

  Mouse thymus lysates, Hela, HUVEC, human tonsil tissue, human placenta tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 10 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3