alpha Actin (cardiac actin) Rabbit Polyclonal Antibody

• Description:

  Actins are highly conserved proteins expressed in all eucaryotic cells. Actin filaments form part of the cytoskeleton and play essential roles in regulating cell shape and movement. Six distinct actin isotypes have been identified in mammalian cells. Each is encoded by a separated gene and is expressed in a developmentally regulated and tissue-specific manner, alpha and beta cytoplasmic actins are expressed in a wide variety of cells; whereas, expression of alpha skeletal, alpha cardiac, alpha vascular, and gamma enteric actins are more restricted to specialized muscle cell type. Smooth muscle alpha actin is of further interest because it is one of a few genes whose expression is relatively restricted to vascular smooth muscle cells. Further more, expression of smooth muscle alpha actin is regulated by hormones, cell proliferation , and altered by pathological conditions including oncogenic transformation and atherosclerosis

• Product Name Alternative:

  ACTC antibody ACTC_HUMAN antibody ACTC1 antibody Actin alpha cardiac muscle 1 antibody Actin antibody alpha cardiac muscle 1 antibody Alpha-cardiac actin antibody ASD5 antibody CMD1R antibody CMH11 antibody LVNC4 antibody

• Abbreviation:

  ACTC1

• Swiss Prot:

  P68032 Human, P68033 Mouse,

• Cellular Locus:

  Cytoplasma , etc.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat, Zebrafish

• Immunogen:

  Synthetic peptide within Human alpha-Actin (cardiac actin) aa 1-50 / 377.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P

• Positive Control:

  Rat heart tissue lysate, Mouse heart tissue lysate, hybrid fish (crucian-carp) heart tissue lysates, human heart tissue, mouse heart tissue, rat heart tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:1,000 ;IHC-P: 1:400

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 42 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4