Crizotinib hydrochloride

• Description:

  inhibitor of the c-Met kinase and the NPM-ALK

• Product Name Alternative:

  (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine hydrochloride

• Field of Research:

  Tyrosine Kinase ALK

• Purity:

  0.9925

• Solubility:

  ≥100.4 mg/mL in DMSO; ≥101.4 mg/mL in EtOH; ≥52.2 mg/mL in H2O

• Smiles:

  C[C@](OC(C=C(C(C=N1)=CN1C2CCNCC2)C=N3)=C3N)([H])C4=C(Cl)C=CC(F)=C4Cl.Cl

• Molecular Formula:

  C21H23Cl3FN5O

• Molecular Weight:

  486.8

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  1415560-69-8