CD127 / IL7R (Marker of T-Reg Cells) (IL7R/2751), 0.2mg/mL

CAT: 0037-BNUB2751-100Size: 1x 100 µLDry Ice: NoHazardous: No
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CAT#:0037-BNUB2751-100Size:1x 100 µL
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Description
The protein encoded by this gene is a receptor for interleukin 7 (IL7) . The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V (D) J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
CD127; IL-7 receptor subunit alpha; IL-7R-alpha; IL7R; IL7RA; IL7R alpha; ILRA; Interleukin 7 receptor alpha chain; Interleukin 7 receptor
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IL7R
Gene ID
3575
NCBI Gene ID
591742; 635723
UniProt
P16871
Swiss Prot
P16871
Host
Mouse
Species Reactivity
Human
Reactivity
CD127|IL7R
Immunogen
Recombinant fragment (around aa 21-236) of human CD127 protein (IL7R) (exact sequence is proprietary)
Target Antigen
CD127 | IL7R
Clonality
Monoclonal
Clone
IL7R/2751
Type
Primary
Source
Animal
Origin
Animal
Applications
WB (verified)
Positive Control
K562, HeLa, Daudi or Jurkat cells. Tonsil, Lymph Node or Spleen.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
52-72 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2c, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA
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