CD3e, Mouse (145-2C11), CF488A conjugate, 0.1mg/mL

CAT: 0037-BNC882013-100Size: 1x 100 µLDry Ice: NoHazardous: No
CAT#:0037-BNC882013-100Size:1x 100 µL
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AVAILABILITY: In Stock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD3 chains. CD3 plays a critical role in TCR signal transduction, T-cell activation, and antigen recognition by binding the peptide/MHC antigen complex. The 145-2C11 antibody is useful for in vitro blocking and activation assays, as well as apoptosis induction and in vivo T-cell depletion. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex) ; CD3e molecule; epsilon (CD3-TCR complex) ; IMD18; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
Cd3e (Mouse)
Gene ID
12501
NCBI Gene ID
210361
UniProt
P22646
Swiss Prot
P22646
Host
Armenian Hamster
Species Reactivity
Mouse
Reactivity
CD3e
Immunogen
H2Kb specific Mouse cytotoxic T lymphocyte clone BM10 37
Target Antigen
CD3e
Clonality
Monoclonal
Clone
145-2C11
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published) |IP (published)
Positive Control
MPBMC's or Thymus or Lymph Node.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
23 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1987) 84:1374-1378. (Flow, IP) Eur J Immunol (1990) 20: 509-515. (functional studies) J Immunol (2003) 171:2496-2503. (Flow; IP; functional studies)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG, kappa
Species
Armenian Hamster, BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A
Product Datasheet
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