Sheep anti Chicken TGF beta II receptor (27-85)

• Background:

  The immunogen used was a recombinant protein containing chick transforming growth factor type II receptor region a.a.27-85. Epithelial-mesenchymal transformation is a critical event in the development of many organ systems including heart. Transforming Growth Factor (TGF ) is one of a number of factors that mediates this transformation. Antibodies directed against TGF Type II receptor block both the endicardial cell activation and subsequent migration that constitute transformation in the chick atrioventricular (AV) cushion.

• Synonyms:

  TGBb Type II r, TGF beta II receptor, transforming growth factor receptor beta, Type II

• UniProt:

  Q90999 (Chicken)

• Host:

  Sheep

• Species Reactivity:

  Chicken

• Isotype:

  IgG

• Type:

  Polyclonal Antibody

• Applications:

  IHC

• Field of Research:

  Inflammation and Immunology

• Purification Method:

  Ammonium Sulfate Precipitation

• Assay Principle:

  Applications: Western Blot (1:100), Immunohistology, Empirical

• Stability:

  See expiration date on vial

• Concentration:

  See vial for Concentration

• Form:

  Provided as solution in phosphate buffered saline with 0,08% sodium azide

• Precautions:

  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.

• References & Citations:

  C. Brown, et. al. (1999) Dev. Dynamics, 1-7

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles

• Functional Analysis:

  WB

• CAS Number:

  9007-83-4