Resveratrol

• Background:

  Resveratrol (also known as SRT-501) is a phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity) ; mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity) ; and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-κB; in a dose- and time-dependent manner.

• Description:

  Resveratrol is a phytoalexin produced naturally by several plants with anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol activates sirtuin subtype 1 (SIRT-1) . SIRT1 activation has been reported to inhibit tumorigenesis and tumor cell proliferation.

• Purity:

  ≥ 98% by HPLC

• Solubility:

  Soluble in DMSO

• Molecular Formula:

  C14H12O3

• Shipping Conditions:

  Room Temperature (continental US) or Gel Packs

• Storage Conditions:

  Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

• Calculated Molecular Weight:

  228.24 Da

• CAS Number:

  501-36-0