ACE Antibody / Angiotensin I Converting Enzyme

• Description:

  This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

• UniProt:

  P12821

• Host:

  Mouse

• Immunogen:

  A portion of amino acids 652-788 from the human protein was used as the immunogen for the ACE antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG2c κ

• Applications:

  WB, ELISA, IHC-P

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Store the ACE antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This ACE antibody is available for research use only.

• CAS Number:

  9007-83-4