PKR-IN-C51
CAT:
804-HY-118131-05
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PKR-IN-C51
- Product Name Alternative: Methophenazine
- CAS Number: 1314594-23-4
- UNSPSC Description: PKR-IN-C51(compound 51) is an ATP-competitive double-stranded RNA-activated protein kinase (PKR) inhibitor with an IC50 of 9 μM. PKR-IN-C51 inhibits intracellular PKR activation in a dose-dependent manner in primary mouse macrophages[1].
- Target Antigen: Ser/Thr Protease
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/pkr-in-c51.html
- Purity: 99.79
- Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: CC(NC1=C2C=CC=C1)=C2C3=NC(NCCC4=CNC5=C4C=CC=C5)=NC=C3
- Molecular Weight: 367.45
- References & Citations: [1]Ruslana Bryk, et al. Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4108-14.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported