MLL5 Antibody (N-term) [APR03921G]

• Background:

  Tissue Location: Widely expressed in both adult and fetal tissues (PubMed:12101424, PubMed:23958951) . Highest levels of expression observed in fetal thymus and kidney and in adult hematopoietic tissues, jejunum and cerebellum (PubMed:12101424, PubMed:23958951) . Isoform NKp44L: Not detected on circulating cells from healthy individuals, but is expressed on a large panel of tumor and transformed cells (PubMed:23958951) .

• Synonyms:

  Histone-lysine N-methyltransferase 2E, Lysine N-methyltransferase 2E, Myeloid/lymphoid or mixed-lineage leukemia protein 5, KMT2E, MLL5

• Gene Name:

  KMT2E

• Gene ID:

  55904

• UniProt:

  Q8IZD2

• Chromosomal Location:

  Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus speckle. Note=Absent from the nucleolus (PubMed:14718661) . Localizes to chromosome during interphase and to centrosomes during mitosis (PubMed:23798402) . Dissociation from mitotic chromosome is likely due to histone H3 phosphorylation on 'Thr-3' and 'Thr-6' (PubMed:23798402) . [Isoform NKp44L]: Cytoplasm. Cell membrane; Peripheral membrane protein

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  23629655241308292379840224130829237984021471866118573682192649652362965523629655

• Molecular Weight:

  204965

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MLL5 Antibody (N-term) [APR03921G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=55904

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8IZD2