PI4KA Antibody (Center) [AMM07186G]

• Background:

  Tissue Location: Expressed ubiquitously. Highest levels in placenta and brain. Little or no expression in lung, liver, pancreas, testis or leukocytes.

• Synonyms:

  Phosphatidylinositol 4-kinase alpha, PI4-kinase alpha, PI4K-alpha, PtdIns-4-kinase alpha, 2.7.1.67, PI4KA, PIK4, PIK4CA

• Gene Name:

  PI4KA

• Gene ID:

  5297

• UniProt:

  P42356

• Chromosomal Location:

  Cytoplasm. Cell membrane Note=Localization to the plasma membrane is mediated by the PI4K complex and association with EFR3 (EFR3A or EFR3B), TTC7 (TTC7A or TTC7B) and FAM126 (FAM126A or FAM126B) (PubMed:23229899) . Localization to the plasma membrane is regulated by TMEM150A (PubMed:25608530)

• Applications:

  WB

• Dilution:

  WB--1:2000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5, - trisphosphate.

• Molecular Weight:

  236830

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PI4KA Antibody (Center) [AMM07186G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5297

• Uniprot URL:

  https://www.uniprot.org/uniprot/P42356