MMEL1 Antibody (N-term) [AMM06416G]

• Background:

  Tissue Location: Predominantly expressed in testis. Weakly expressed in brain, kidney and heart.

• Synonyms:

  Membrane metallo-endopeptidase-like 1, Membrane metallo-endopeptidase-like 2, NEP2 (m), Neprilysin II, NEPII, Neprilysin-2, NEP2, NL2, Membrane metallo-endopeptidase-like 1, soluble form, Neprilysin-2 secreted, NEP2 (s), MMEL1, MELL1, MMEL2, NEP2

• Gene Name:

  MMEL1

• Gene ID:

  79258

• UniProt:

  Q495T6

• Chromosomal Location:

  Membrane; Single-pass type II membrane protein. Secreted. Note=A secreted form produced by proteolytic cleavage also exists.

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond (By similarity) .

• Molecular Weight:

  89367

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MMEL1 Antibody (N-term) [AMM06416G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=79258

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q495T6