Biotinylated Human ASGR1 / ASGPR1 Protein, His, Avitag™

• Background:

  ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes. The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2) . ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.

• Description:

  Biotinylated Human ASGR1 Protein, His, Avitag (GS1-H82Q3) is expressed from human 293 cells (HEK293) . It contains AA Gln 62 - Leu 291 (Accession # P07306-1) .

• Specifications:

  This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 33.4 kDa. The protein migrates as 40-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

• Accession Number:

  P07306-1

• Expression Region:

  Gln 62 - Leu 291

• Host:

  HEK293

• Target:

  ASGR1

• Conjugation:

  Biotin-labeled

• Tag:

  N-10xHis & N-Avi

• Source:

  Human

• Stability:

  ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

• Endotoxin:

  1.0 EU per μg

• Purity:

  95%

• Format:

  Powder

• Buffer:

  PBS, 0.2 M Arginine, pH7.4

• Additives:

  Trehalose

• Molecular Weight:

  33.4 kDa

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C

• Package Size:

  200ug*1

• Species:

  Human