Anti-CD1b (T-Cell Surface Glycoprotein) Monoclonal Antibody

• Background:

  The Mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.

• Description:

  Boster Bio Anti-CD1b (T-Cell Surface Glycoprotein) Monoclonal Antibody (Catalog # M02158) . Tested in ELISA, Flow Cytometry, IF applications. This antibody reacts with Human.

• Synonyms:

  T-cell surface glycoprotein CD1b; CD1b; CD1B

• Gene Name:

  CD1B

• UniProt:

  P29016

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Human peripheral lymphocytes

• Clonality:

  Monoclonal

• Clone:

  Clone: Clone: RIV12

• Tissue Specificity:

  Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

• Applications:

  ELISA, Flow Cytometry, IF

• Field of Research:

  Adaptive Immunity, B Cells, Cell Type Markers, Immunology, Non-CD

• Purification:

  200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

• Concentration:

  Purified antibody with BSA and azide at 200ug/ml

• Form:

  Liquid

• Function:

  Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. .

• Molecular Weight:

  36939 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Fragment:

  IgG1, kappa

• Other Gene Names:

  T-cell surface glycoprotein CD1b

• Subcellular Location:

  Cell surface