Anti-Human IBA1 AIF1 Antibody

• Description:

  Boster Bio Anti-Human IBA1 AIF1 Antibody catalog # M01394-2. Tested in IF, IHC, WB applications. This antibody reacts with Human.

• Synonyms:

  Allograft inflammatory factor 1; AIF-1; Ionized calcium-binding adapter molecule 1; Protein G1; AIF1; G1, IBA1

• Gene Name:

  AIF1

• UniProt:

  P55008

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Peptide identical to part of the C-terminal of human IBA1 coupled to KLH

• Clonality:

  Polyclonal

• Tissue Specificity:

  Detected in T-lymphocytes and peripheral blood mononuclear cells. .

• Applications:

  IF, IHC, WB

• Field of Research:

  Actin Binding Proteins, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

• Concentration:

  0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Dilution:

  WB: 1:1,000-5,000. IF 1:2,000-5,000

• Function:

  Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. .

• Molecular Weight:

  16703 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Allograft inflammatory factor 1

• Subcellular Location:

  Cytoplasm, cytoskeleton . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, phagocytic cup . Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. .