Anti-HLA-Aw32 & HLA-A25 (MHC I) Monoclonal Antibody

• Background:

  This monoclonal antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T-cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This monoclonal antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.

• Description:

  Boster Bio Anti-HLA-Aw32 & HLA-A25 (MHC I) Monoclonal Antibody (Catalog # M00194) . Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human.

• Synonyms:

  HLA class I histocompatibility antigen, B-7 alpha chain; MHC class I antigen B*7; HLA-B; HLAB

• Gene Name:

  HLA-A

• UniProt:

  P01889; P30443; P30499

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, Cw-, DR2, DRw10

• Clonality:

  Monoclonal

• Clone:

  Clone: Clone: SPM417

• Applications:

  Flow Cytometry, IF, IHC

• Purification:

  200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

• Concentration:

  Purified antibody with BSA and azide at 200ug/ml

• Form:

  Liquid

• Function:

  Involved in the presentation of foreign antigens to the immune system.

• Molecular Weight:

  40460 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Fragment:

  IgG2a, kappa

• Other Gene Names:

  HLA class I histocompatibility antigen, B-7 alpha chain

• Subcellular Location:

  Cell Surface