Anti-MRPL50 Antibody

• Background:

  Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.
  
  Ota T., Nat. Genet. 36:40-45(2004).
  Humphray S.J., Nature 429:369-374(2004).
  The MGC Project Team; Genome Res. 14:2121-2127(2004).

• Description:

  Boster Bio Anti-MRPL50 Antibody (Catalog # A17223) . Tested in WB applications. This antibody reacts with Human.

• Synonyms:

  39S ribosomal protein L50, mitochondrial; L50mt; MRP-L50; MRPL50

• Gene Name:

  MRPL50

• UniProt:

  Q8N5N7

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthesized peptide derived from internal of human MRPL50.

• Clonality:

  Polyclonal

• Applications:

  WB

• Field of Research:

  DNA/RNA, Epigenetics and Nuclear Signaling, Mito. Translation, Ribosome, Translation

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Dilution:

  Western blotting: 1:500~1:3000

• Form:

  Liquid

• Molecular Weight:

  18325 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  39S ribosomal protein L50, mitochondrial

• Subcellular Location:

  Mitochondrion .