Anti-Cyclin A CCNA2 Antibody

• Background:

  Anti-Cyclin A detects Cyclin A. Cyclin A is a member of the cyclin family. Cyclin A binds to S phase Cdk2 and is required for the cell to progress through the S phase. Cyclin A/ Cdk2 is inhibited by the complex p21CIP. Anti-Cyclin A Antibody is ideal for investigators involved in Cell Signaling, cell biology and Signal Transduction research.

• Description:

  Boster Bio Anti-Cyclin A CCNA2 Antibody (Catalog # A00700) . Tested in IHC, WB applications. This antibody reacts with Human.

• Synonyms:

  Cyclin A, CCN1, CCNA, CCNA2, Cyclin A2

• Gene Name:

  CCNA2

• UniProt:

  P20248

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Anti-Cyclin-A Antibody was produced by repeated immunizations with a recombinant protein corresponding to the human cyclin A.

• Clonality:

  Polyclonal

• Applications:

  IHC, WB

• Field of Research:

  Cancer, Cardiovascular, Cell Biology, Cell Cycle, Epigenetics and Nuclear Signaling, Lipids/Lipoproteins

• Purification:

  Anti-Cyclin A was prepared from monospecific antiserum by delipidation and defibrination. Antiserum will specifically react with a 60 kDa Cyclin A protein from human, rat and mouse tissue. No reaction was observed against other related cyclins. Cross-reactivity with Cyclin A from other species may also occur.

• Concentration:

  80 mg/mL by Refractometry

• Form:

  Liquid (sterile filtered)

• Function:

  Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.

• Molecular Weight:

  48551 MW

• Shipping Conditions:

  Due to dry ice shipping issues, this product is temporarily not available to distributors outside of the United States.

• Storage Conditions:

  Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

• Fragment:

  Antiserum

• Applications Notes:

  Anti-Cyclin-A antibody has been tested by western blot and immunohistochemistry and is suitable for the detection by immunoblot, ELISA, IHC, and IP of human, rat and mouse Cyclin A. Researchers should determine optimal titers for applications that are not stated below.

• Other Gene Names:

  Cyclin-A2

• Subcellular Location:

  Nucleus. Cytoplasm. Cytoplasmic when associated with SCAPER.