Mouse Tissue Factor/F3 ELISA Kit PicoKine®

• Background:

  Tissue factor, also called platelet tissue factor, factor III, thrombokinase, or CD142 is a protein present in sub endothelial tissue and leukocytes necessary for the initiation of thrombin formation from the zymogene prothrombin. Tissue factor gene was mapped to 1pter-p21 by study of somatic cell hybrids with a species-specific sensitive chromogenic assay. This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII.

• Description:

  Mouse Tissue Factor/F3 ELISA Kit PicoKine® (96 Tests) . Quantitate Mouse F3 in cell culture supernatants, serum, plasma (heparin, EDTA, citrate) and cell lysates. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Synonyms:

  Tissue factor; TF; Coagulation factor III; CD142; F3; Cf-3, Cf3

• Gene Name:

  Tissue factor

• UniProt:

  P20352

• Reactivity:

  Mouse

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: NS0; Immunogen sequence: A29-E251

• Applications:

  ELISA

• Field of Research:

  Cardiovascular

• Sample Type:

  Cell culture supernatants, serum, plasma (heparin, EDTA, citrate) and cell lysates.

• Detection Range:

  15.6 pg/ml - 1,000 pg/ml

• Sensitivity:

  <10 pg/ml

• Function:

  Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.

• Storage Conditions:

  Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Other Gene Names:

  F3

• Subcellular Location:

  Membrane; Single-pass type I membrane protein.

• Protein Name:

  Tissue factor