[Glp6] Substance P (6-11)

• UNSPSC Description:

  [Glp6] Substance P (6-11) is an analogue of substance P (6-11). Substance P (6-11) stimulates [3H]-inositol monophosphate ([3H]-IP1) formation in rat urinary bladder by acting on the 'septide-sensitive' tachykinin receptors[1][2].

• Target Antigen:

  Neurokinin Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/glp6-substance-p-6-11.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H]2NC(CC2)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O

• Molecular Weight:

  723.88

• References & Citations:

  [1]Brzezinski P M, Godlewski A. The effect of caltitonin, somatostain and analogue (Glp6) of substance P (6-11) on chemotaxis and phagocytosis of guinea pig heterophilis in vitro. Folia Histochemica et Cytobiologica, 1991, 29(4).|[2]Torrens Y, et al. Substance P(6-11) and natural tachykinins interact with septide-sensitive tachykinin receptors coupled to a phospholipase C in the rat urinary bladder. Neuropeptides. 1997 Jun;31(3):243-51.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  61123-13-5