Ac-Arg-Gly-Lys-AMC

• UNSPSC Description:

  Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

• Target Antigen:

  Fluorescent Dye

• Type:

  Peptides

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ac-arg-gly-lys-amc.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC=C(NC([C@H](CCCCN)NC(CNC([C@@H](NC(C)=O)CCCNC(N)=N)=O)=O)=O)C=C1O2)=CC2=O

• Molecular Weight:

  558.63

• References & Citations:

  [1]Noonepalle S, et, al. Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models. J Med Chem. 2020 Sep 24;63(18):10246-10262.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  660846-99-1