Interleukin 6 Receptor subunit beta Antibody / IL6ST / CD130

• Description:

  IL6ST is a signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways. [UniProt]

• UniProt:

  P40189

• Host:

  Mouse

• Immunogen:

  A recombinant fragment of the human protein corresponding to the extracellular domain was used as the immunogen for the Interleukin 6 Receptor subunit beta antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG2b κ

• Applications:

  IHC-P

• Format:

  Purified

• Buffer:

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Reconstitution:

  Aliquot the Interleukin 6 Receptor subunit beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Interleukin 6 Receptor subunit beta antibody is available for research use only.

• CAS Number:

  9007-83-4